Associate Research Scientist Cell Culture

Profile

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

Summary: The Biochemistry, Cell Biology and Molecular Pharmacology group in Cambridge is dedicated to working closely with chemistry colleagues in discovering novel small molecule therapeutics for immunological & neurological diseases and overcoming cancer resistance. Our primary role is to develop and apply robust biochemical and cell biology tools that enable small molecule drug discovery. These critical components of the drug discovery process provide in vitro data that guide early discovery and underpin their performance in preclinical disease settings. The data generated ultimately allows selection of drug candidates and forms an essential element in IND filings with the FDA for clinical development.

Description: BMS is seeking a highly motivated individual with expertise in mammalian cell culture to join the Leads Discovery and Optimization group supporting multiple disease areas across R&D. This individual will culture cell lines to support a range of R&D functions including high-throughput screening, lead optimization, and target validation. Working as part of interdisciplinary teams, this role involves all aspects of culture maintenance, transfection, selection of stable cell lines, cell line characterization, and QC. The ideal candidate will be experienced in standard molecular biology techniques and automated cell culture as well as have hands-on experience working with recombinant cell lines, primary cells, and stem cells including iPSCs.

Duties and Responsibilities:

Mammalian Cell culture: cell seeding, splitting, harvesting, plating and banking

PBMC and primary immune cell preparation and expansion

Developing SOPs for newly acquired cell lines

Interface with customers to provide cellular reagent requests and trouble-shooting assistance

Cell culture QC and analysis: cell density, cell viability, growth profiling, purity and cell surface marker expression

Cell inventory management

Transient transfection and cell harvesting

Operation of automated cell culture robotic platforms

Key experiences and qualities:

Extensive cell culture experience

Ability to master new skills, methods and technologies is essential

FACS analysis/sorting experience is highly desirable

Self-driving, able to conduct daily work with minimum supervision

Organized, able to maintain and track multiple interspersed activities

Excel at trouble shooting and creative solutions to solve technical challenges

Detail oriented with good record-keeping skills

Comfortable working in a fast-paced environment with fixed timelines

Good communication and interpersonal skills, at ease with other team members & collaborators

Qualifications:

BS or MS degree in biology or related field

2-5 years of laboratory experience post baccalaureate

Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

Company: Bristol-Myers Squibb

Req Number: R1524809_EN

Updated: 2020-05-29 00:00:00.000 UTC

Location: Cambridge,Massachusetts

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.

Company info

Bristol-Myers Squibb Company
Website : http://www.bms.com